Gene expression is a fundamental process of living cells that brings the genetic information stored in the DNA to life. The overall goal of the lab is to unravel, how this information is “read” by the cell. The DNA is first transcribed into messenger (m)RNA. The mRNA is processed and packaged by proteins into an mRNP. We focus on the question, how nuclear mRNP formation takes place, how it is integrated with concurrent steps of gene expression and how it influences subsequent life of the mRNA.