Pharmaceutical industry

Biofabrication refers to the controlled production of biological structures, tissues and materials using combined processes from biotechnology, engineering and materials science. Through the use of cell-based systems, biomimetic materials and digitally controlled manufacturing technologies, it is possible to develop biological systems in a targeted manner, design them to be functional and manufacture them on a scalable basis.

Two antenna-like feelers turn unicellular microalgae into fantastic swimmers. Two researchers from the Max Planck Institute for Intelligent Systems have harnessed this ability. They transformed the organisms into mini-robots that could be used as drug transporters in medicine, for example.

The manufacture of pharmaceutical and biotech products is usually associated with high material consumption. For this reason, the Giessen-based start-up Green Elephant Biotech has developed recyclable cell culture vessels. These not only reduce the carbon footprint by up to 90% compared to conventional disposable items, but also improve the growth conditions of the cells. This solution is now being further developed in a strategic partnership with the family-owned company Bürkert Fluid Control Systems.

So-called antigen tests have been common knowledge since the coronavirus pandemic at the latest. They have long been used in medical diagnostics to detect certain viruses in saliva, blood or urine. However, the antibodies required for this are largely derived from animal cells or living animals. Now the Hanover-based start-up Phaeosynt wants to produce antibodies from algae. The German Federal Environmental Foundation (DBU) is funding the project with 125,000 euros.

In biotechnology, microorganisms have long been used to manufacture products for medicine, agriculture or the chemical industry or to boost industrial processes. However, bacteria are also becoming increasingly important in the diagnosis and treatment of diseases. New possibilities could now open up in the biotechnological application of bacteria. Researchers at the University of Bayreuth have laid the foundation.

Bringing more good ideas into application and thus to companies and people: As a new component of its transfer and innovation promotion programme, the Federal Government intends to promote social and technological innovations in the future by setting up the German Agency for Transfer and Innovation (DATI). As an innovation agency, DATI will be based in Erfurt.

Thanks to a mix of methods, a team at the Technical University of Braunschweig has succeeded for the first time in identifying individual amino acids in a peptide by analyzing the surface of the molecule under a microscope. This means that one of the basic building blocks of life can now be examined down to the nanometer.