Natural plant substance from microbes

Nature offers a wide range of active ingredients that play an increasingly important role in medicine, the pharmaceutical and food industries. Natural substances that are not very popular are gradually coming into the spotlight. Ferulic acid is one of these candidates. It is contained in many plants such as rice, dill or roseroot and has health promoting ingredients as well as flavours which are relevant for the production of aromas such as vanillin and the typical wheat beer taste.

Advancing green methanol synthesis

Every year the chemical industry produces around 100 million tonnes of methanol. However, the production of this important basic chemical is based on fossil raw materials and causes high CO2 emissions. The exact opposite would be conceivable: Methanol can also be produced from green hydrogen and carbon dioxide. But process requirements for producing green methanol on an industrial scale have been little researched to date. The project "Power-to-Methanol - Grünes Methanol", funded by the Federal Ministry of Economics, wants to change this.

More research to protect biodiversity

"The decline of biodiversity and intact ecosystems in Germany is alarming." With these words, Federal Research Minister Anja Karliczek summed up a development that the Federal Ministry of Education and Research is counteracting with an initiative for the conservation of species diversity. On the occasion of the International Day of Biological Diversity, the ministry is now providing a further 25 million euros for research projects aimed at protecting biodiversity.

Biocatalyst for new drugs

For many years, medicine has been looking at many molecules from nature, but usually these compounds are so complex that it is difficult to chemically replicate them. If they do succeed, the basis for this is ultimately petroleum-based chemistry. In nature, by contrast, enzymes produce these complex molecules. One of these enzymes is the enzyme AmbDH3, which a team led by Frank Hahn has now investigated in greater detail. This enzyme is involved in the formation of Ambruticin, a suspected fungicide in bacteria.

Bioprocess developed for plant hormone

Scientists at Bielefeld University have succeeded for the first time in enzymatically producing 12-oxophytodienoic acid (12-OPDA), a central precursor of the plant hormone jasmonic acid. The jasmonates are derived from the acidity, by means of which plants react to injuries, warn each other of pests or also control fruit ripening: "For example, jasmonic acid can trigger the release of toxic substances such as nicotine in the leaves, which harm the attackers", explains biologist Karl-Josef Dietz.

Vanilla aroma from lignin

Vanillin gives the vanilla bean its characteristic flavor. It is one of the most frequently used flavoring substances in food and perfume production, but also in the production of pharmaceuticals. Several tens of thousands of tons are used annually. Until now, however, artificially produced vanillin has been made from petroleum, creating toxic waste. Researchers at the Johannes Gutenberg University in Mainz (JGU) have now succeeded in developing a sustainable method for obtaining the coveted aroma substance. A team led by Siegfried Waldvogel u