Biotechnology/Systems biology

Optimising protein structures with AI

Alongside fats and carbohydrates, proteins are the main nutrients that the human body needs. Proteins serve as a building material for cells and tissue, can repair bones and tissue or control metabolic processes in the body as an enzyme. Researchers have therefore been endeavouring for years to recreate proteins on the computer and give them better properties. An international research team led by the Technical University of Munich (TUM) has now developed a new method for designing proteins. 

Electrochaea takes bio-methane to Japan

Electrochaea GmbH is using a promising technology to make the production and, above all, storage of sustainably produced gas even more efficient. It involves microorganisms that are billions of years old, known as archaea, which act as biocatalysts in the conversion of electricity into gas. Following demonstration plants in Denmark, Switzerland and the USA, a biomethanisation plant will now also be built in Japan. According to Electrochaea, a corresponding five-year licence agreement has been concluded with the Japanese energy company Hitachi.

Antibodies from diatoms for diagnostics

So-called antigen tests have been common knowledge since the coronavirus pandemic at the latest. They have long been used in medical diagnostics to detect certain viruses in saliva, blood or urine. However, the antibodies required for this are largely derived from animal cells or living animals. Now the Hanover-based start-up Phaeosynt wants to produce antibodies from algae. The German Federal Environmental Foundation (DBU) is funding the project with 125,000 euros.

“With communication standards to a digital biotech lab”

Engineer Felix Lenk is the founder and Managing Director of SmartLab Solutions GmbH. The spin-off from Dresden University of Technology develops hardware and IT solutions for the digitalised and automated laboratory of the future. These include the ‘Sens-o-Spheres’, a mobile measuring system the size of a pea that records important process parameters such as temperature in the culture medium of a bioreactor and transmits them to a base station.

Securing food supplies with new wheat varieties

Wheat is one of the most important food crops in the world and is dependent on a supply of nitrogen. In agriculture, nitrogen is therefore applied in the form of fertiliser to promote plant growth and achieve good yields. However, the right amount is important. Nitrogen that the plant cannot process ends up in the environment and pollutes ecosystems. But how can the supply of wheat be secured without further harming the environment?

Synthetic biology: Designing microbial communities

Microorganisms such as bacteria, fungi and viruses never act alone. They form communities, interact and thus have a significant influence on humans and nature. One example of this is the microbial community in the human gut, the so-called microbiome. It is only through the interaction of microorganisms that nutrients are metabolised and made usable for the body. However, if the microbiome is composed incorrectly, this can lead to health problems.