Biotechnology/Systems biology

3D skin models to reduce allergens

The skin is the largest organ of the human body and fulfils a number of vital functions. However, the skin is also under constant “attack” – by the sun, water or allergens in clothing and cosmetics. In order to minimise or even exclude allergens in such products, they are tested on skin models in cell culture. For a better understanding of skin physiology the Mannheim University of Applied Sciences (MUAS) and BRAIN AG are developing a new three-dimensional skin model with the aim to provide new insights for health care and cosmetic applications.

ERC funding for pioneering plant research

Whether pathogenic fungi or rising temperatures: plants are increasingly suffering the consequences of climate change, putting pressure on agriculture as a food sector. What mechanisms have plants developed to protect themselves against pests or changing environmental conditions? Marburg biochemist Gert Bange and Brandenburg molecular biologist Philip Wigge are addressing precisely these questions. The two scientists have now been awarded the prestigious ERC grant from the European Research Council for their pioneering research.

Discovering new sources of protein

Proteins form an important part of our diet. The vast majority of vital nutrients are still covered by animal protein sources such as meat. Yet factory farming, pesticide use and climate change are increasingly endangering soils and groundwater and putting pressure on agriculture. The switch to new protein sources can be a solution. This is where the FutureProteins project comes in. Researchers from six Fraunhofer institutes are working together to develop novel protein sources as an alternative to meat and turn them into new food products.

Polishing up synthetic fibres with enzymes

This is hoped to assist in the development of innovative products for the textile industry and for construction chemistry. Thereby, newly discovered enzymes will be employed to targetedly modify natural products or synthetic fibres and to equip them with useful properties. To pursue these goals, the nine partners from industry and higher-education research have a total of €8 million up to 2018, half of which is managed by the Federal Ministry of Education and Research (BMBF) in the context of  ‘Innovation Initiative Industrial Biotechnology’.

Precious single cell oils born of waste water

Today, the strategic alliance ‘ZeroCarbonFootprint – ZeroCarbFP’ is exploring the ways in which this hidden potential could be recovered. The twelve participating partners in the alliance, which officially began work in 2013, are hunting for microorganisms that can use the carbon-rich wastes as substrates and in the process convert them into valuable building blocks and substances for industry.

Biological protective sheathing for teeth

Recorded as the oldest species on the planet, scientists have discovered a bio-silicate in sponges that can be used for new kinds of medical coatings, for example in dentistry or for bone implants. Supported by the Federal Ministry of Education and Research (BMBF), the company NanotecMARIN GmbH has pushed forward the development of biotechnological production processes for the material. The first tests on patients are set to begin.

Natural substances to mask bitter tastes

The focus of the strategic alliance “Natural Life Excellence Network 2020” (NatLifE 2020) is the new generation of biological active ingredients for healthy food and cosmetics products. Headed by Brain AG – a German biotech corporation from Zwingenberg in Hessen, 22 partners from economy and universities have come together to advance the research, development and production of natural ingredients.

Making methanol from biomass

Methanol is one of the chemical industry’s most important source materials. It is colourless, flammable and smells of alcohol, and the starting point for manufacturing paints and varnishes as well as fuel. In 2015, the global demand for methanol was about 65 million tonnes. However, this compound of carbon monoxide, water and oxygen is produced mainly from finite resources such as mineral oil, natural gas or coal.