Biotechnology/Systems biology

Pentylene glycol is a moisturizing agent that is contained in almost all creams. The divalent alcohol is odorless and colorless. Compared to the common alcohol ethanol, the so-called diol ensures that the skin optimally binds moisture and active agents. At the same time, it acts as an antimicrobial and thus keeps bacteria away. Pentylene glycol is therefore a natural preservative. To date, however, pentylene glycol has been obtained almost exclusively from natural gas and crude oil.

Disposable plastic products are to disappear from the European market from 2021. This was decided by the EU Parliament in November 2018. Since then, more research has been conducted into alternatives to disposable plastic articles such as drinking straws or cutlery that are affected by the ban. Two master's graduates of the SRH University of Applied Sciences in Heidelberg have a tasty solution to the problem: they are developing edible spoons.

CRISPR-Cas9 has revolutionized molecular biology. The enzymatic system works like scissors that can cut DNA at a defined location to deactivate genes or insert new gene sequences. To make sure that CRISPR-Cas9 finds the right place to cut, it is combined with a target-specific so-called guide RNA. However, even this guide RNA makes a certain percentage of mistakes in finding the target.

In order to detect acute infection with the corona virus, thousands of tests based on the polymerase chain reaction (PCR) are performed daily. With the help of this molecular copy method, the genetic material of the virus, which consists of the biomolecule ribonucleic acid (RNA), is detected in the swabs. The few virus RNA molecules are first transcribed into DNA and then amplified by the PCR in numerous copy cycles. Only then can the existence of the viral genetic material in the samples be determined. Experts refer to this as real-time RT-PCR.

Satellite data have long since expanded their use beyond weather forecasting. They provide agricultural researchers with important information on soil properties or plant growth and are the basis for harvest forecasts. Data collected from orbit are also an important tool for marine researchers to observe algae growth. Up to now, satellites have been used to measure the amount of the plant pigment chlorophyll in the water and thus the concentration of algae.

Scientists have copied many a fine chemical from nature. Phenylglycine is also a substance produced by bacteria. However, there are two mirror-image forms of it - L-phenylglycine and D-phenylglycine. The former is the product of microorganisms, the latter is a medically highly interesting compound, which as yet can only be produced conventionally in a petrochemical process - until now.

Many plants and animals have adapted to their environment during evolution. The gradual change of the genetic make-up took place over generations. The gradual change of the genetic material took place over generations. But climate change is becoming a problem for many organisms because it is progressing too rapidly. As part of an international study, researchers at the GEOMAR Helmholtz Centre for Ocean Research Kiel have now investigated how strongly epigenetic processes influence the adaptability of organisms to the environment.

Plant residues are ideal raw materials for biobased alternatives to products of the petroleum industry: They do not compete with the cultivation of food and animal feed and promise additional added value to the plant products already produced. In practice, there is often a difficulty: the microorganisms used in biotechnology usually cope with only one of the two varieties of sugars, which are found in vegetable residues.

Plants need water to grow. The supply of liquid is provided by the roots. How much water is absorbed is determined by a hydraulic system that works similar to machines. A negative pressure ensures that plants suck the water out of the soil. The suction power is based on the negative pressure in the plant supply channels, which is created by the evaporation of water on the cell walls of the leaves. But the pressure in this network is usually limited to minus 100 bar for plants. Until now it was unclear why this is so.

Nature offers a wide range of active ingredients that play an increasingly important role in medicine, the pharmaceutical and food industries. Natural substances that are not very popular are gradually coming into the spotlight. Ferulic acid is one of these candidates. It is contained in many plants such as rice, dill or roseroot and has health promoting ingredients as well as flavours which are relevant for the production of aromas such as vanillin and the typical wheat beer taste.